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Cortical lesions on MRI in MS |
CONCLUSIONS: In this cohort of patients with early-stage MS, cortical demyelinating lesions were frequent, inflammatory, and strongly associated with meningeal inflammation.#
"This study supports MRI findings and what we know about cognitive impairment in early MS. 30-50% of subjects with CIS (first demyelinating event) have significant cognitive impairment. I am not sure that this study provides any new insights, except cortical lesions are not associated with Dawson's fingers; their morphology is very different to white matter lesions. Understanding gray matter cortical lesions is clearly very important and area of active research. "